See Press Release #13 New Proteque Non-Steroid Approach for Eczema Children At San Francisco Pediatric Conference.

See Press Release #12 Proteque Seeking M&A or Private Equity Partner in New Approach to Eczema.

See Press Release #11 Eczema Education Guide for Parents and Physicians Focuses on Prevention - Free.

See Press Release #10 Non-Steroid Approach to Manage Eczema for Children and Physicians Presented At National Pediatric Conferences by Raleigh NC Dermatology Company.

See Press Release #9 New Proteque Non-Steroid Approach for Eczema Children Introduced at Boston Pediatric Conference.

See Press Release #8 Proteque's Steroid-Sparing Approach for Eczema Sufferers.

See Press Release #7 Father’s Internet Search Finds Solution for Daughter’s Suffering.

See Press Release #6 UCSF Researchers Report on Non-Steroid to Prevent Dermatitis at AAD

See Press Release #5 New Non-Corticosteroid Proteque Lotion to Reduce Skin Irritation and UVB Sun Damage Presented by Skin Expert at Hawaii Conference.Conference.

See Press Release #4 Proteque talks "skin sense" on TV in PA.

See Press Release #3 Medecon Introduces To Its Members Protèque  For Hand Eczema And Irritant Contact Dermatitis For Staff And Patients.

See Press Release #2 Diversified Network Services (DNS) Announces Contract Award To New Contact Dermatitis Disease Management Company-- Proteque International.

See Press Release #1 Clinical Study Proves new skin protectant to be compatible with antimictobial scrub soaps used in hospitals.

 

Press Release #13

NEW PROTEQUE NON-STEROID APPROACH FOR ECZEMA CHILDREN AT SAN FRANCISCO PEDIATRIC CONFERENCE

RALEIGH, N.C., Nov. 1 /PRNewswire/ -- US and international pediatricians attended the American Academy of Pediatrics (AAP) national Conference and discussed with Proteque International their successful use of non-steroid, Proteque(R) SPS to manage eczema and dermatitis patients. More than 5,500 pediatricians and other health care professionals attended this premier pediatric educational event in San Francisco.

Eczema (sometimes called dermatitis) is easy to diagnose--itchy, red, dry, peeling skin, sometimes with cracks or rash. It is incredibly itchy, sensitive, stings, burns and the pain makes babies and children (and some adults) cry and scratch. "Over 5000 eczema and dermatitis specialists from dermatology, neonatology, ENT, pediatric allergists, and pediatric departments reported positive outcomes in actual patient use with this new steroid-sparing approach," said Fred Brachman, President and CEO of Proteque International. "Most common types of patient conditions were pediatric eczema, skin allergies and atopic and contact dermatitis including perioral (around the mouth), face and body." The once-a-day, water-resistant dimethicone-based Proteque formula, with four non-steroid anti-inflammatory and long-lasting antibacterial ingredients, reduces erythema and transepidermal water loss, and killed Staph. Aureus and E.Coli according to controlled clinical studies at UCSF Department of Dermatology and NCSU.

One attendee at the AAP conference, Dr. Derrina Wu, in private practice in San Francisco, reported four days later, "I actually tried the product on my daughter who has atopic dermatitis. The instant soothing effect on her irritated skin without the hydrocortisone and with all natural ingredients was what impressed me and made me a believer in the product. I have begun to recommend it to several patients."

Brachman said, "Proteque is recommended alone with no steroids, or as combination therapy with a lower potency corticosteroid. Pediatricians, allergists and dermatologists prefer to prevent the recurrence of eczema and dermatitis instead of repeated use of debilitating strong topical or oral corticosteroids and antibiotics. These can cause thinning of the skin, scaring, osteoporosis and growth problems for children. No prescription is required and the product contains no steroids or immunosuppressants such as tacrolimus."

Proteque SPS (pronounced Pro-teck) is available now online at Drugstore.com, CVS.com, Sanavita.com (International orders outside US), natlallergy.com. Also available at over 250 Dermatologist, Allergist & Pediatrician Offices or can be ordered in 24 hours at over 40,000 independent, and chain pharmacies, such as Wal-Mart, KMart, Walgreens, Kroger, Rite-Aid, Long's, Osco, Eckerd's, Sav-On, Safeway, and CVS.

More information, including clinical research, educational and ordering information is at www.proteque.com or 800-953-9250. Proteque International's mission is to provide safer integrated solutions for eczema and dermatitis sufferers as recommended by Pediatric, Dermatology, Family Practice, OBGYN and Allergy physicians.

Contact: Fred Brachman, Pres. & CEO 800-953-9250 or info@proteque.com

 

Press Release #12

PROTEQUE SEEKING M&A OR PRIVATE EQUITY PARTNER IN NEW APPROACH TO ECZEMA

Click here to listen to the interview.

RALEIGH, N.C., Feb. 21 /PRNewswire/ -- Healthcare Industry Senior Analyst, Tan Khandaker, MD, interviewed CEO Fred Brachman about Proteque International strategic plans and M&A interests. The Wall Street Reporter (http://www.wallstreetreporter.com ) is a widely recognized source of business intelligence for the financial and M&A community looking for private acquisitions and investments.

Private equity investors, business development, mergers and acquisition, and product managers involved in skin-related drug delivery systems and consumer products should be interested in this company for its unique integrated product platform for eczema and dermatitis and its synergies with the allergy and immunology markets.

Highlights:

1. Eczema and dermatitis are two of the fastest growing disease categories being reported in the pediatric, allergy, immunology, diabetic and dermatology markets affecting an estimated 20 percent of all children and 20-40 percent of adult males and females.

2. The Proteque(R) brand has developed a growing base of over 10,000 US physicians recommending its first OTC product, Proteque SPS Skin Protection System -- using a unique integrated platform of botanicals, protectant and antibacterial ingredients for a steroid-sparing preventive approach to managing eczema and preventing a variety of skin conditions generally called dermatitis. The first OTC product is already on the market through pharmacies, Internet, and over 200 Dermatologist, Plastic Surgeon and Allergist Offices.

3. Fred Brachman, CEO and a management consultant specializing in consumer and pharmaceutical product marketing and portfolio planning, believes current delivery systems technology companies such as ALZA, Elan, Atrix and consumer product companies such as Procter & Gamble, Beiersdorf,
L'Oreal, Schering-Plough and Colgate Palmolive could increase significantly their portfolio valuation by integrating his company's unique integrated approach to disease management and prevention. He
believes consumer Healthcare-oriented companies are missing a significant opportunity to apply an integrated platform approach to more cost effective delivery systems, portfolio development and channel management, and product and brand extension strategies -- as IT market
leaders learned are the keys to economic success in the last 20 years.

4. Proteque International is actively seeking private equity investment bankers or a merger & acquisition candidate with existing portfolio assets and investments in dermatology, allergy, or immunology, particularly in pediatric and consumer Healthcare products.

The Proteque web site, www.proteque.com, contains extensive information about the company management, clinical research, press releases, product description, education for physicians and consumers, and informative newsletter articles by pediatricians and dermatologists.

Proteque will be an exhibitor at the American Academy of Dermatology meeting March 3-6 in Washington, DC.

Proteque's mission is to help physicians bring safer and more cost effective solutions to eczema, allergy and immune deficiency patients (babies, children and adults) suffering with serious skin conditions.

 

Press Release #11

ECZEMA EDUCATION GUIDE FOR PARENTS AND PHYSICIANS FOCUSES ON PREVENTION- FREE

RALEIGH, N.C., Jan. 16 /PRNewswire/ -- A newly published "Eczema Education
Guide for Parents and Physicians" explains that, while there is no cure for
eczema, there are more effective and safer methods of prevention -- with less
or no steroids. As many as 10 to 20 percent of all infants suffer from eczema, according to one research study cited in the paper. Older children, adolescents and adults all suffer with hand or body eczema or dermatitis at some time in their lives, and at least two-thirds of those affected the
most are females.

"What Every Family With Eczema Should Know -- Eczema Education Guide for Parents and Physicians" will be distributed to over 500 Pediatricians, Neonatologists, Allergists and Pediatric Dermatologists attending the Masters of Pediatric Dermatology, Jan. 17-22. It is available to consumers, physicians, and healthcare editors free at www.proteque.com.

The editor, Patty Brachman, is a registered nurse and Vice President, Professional and Consumer Education, Proteque International in Raleigh, NC. As a surgical nurse, mother and now grandmother with eczema, she dedicated her career to developing a safer, more effective non-steroid preventive solution and education for sufferers like herself. Five years ago she founded her company with that mission. Now, her new steroid-sparing preventive maintenance approach, as explained in the guide, has been adopted
and is being recommended by over 10,000 pediatricians, family practice, dermatologists, podiatrists and allergists throughout the US. The first 1,000 people who tried Proteque's steroid sparing strategy were doctors and nurses suffering with chronic hand eczema or members of their family with
eczema. Now over 70% are pediatric eczema patients and at least one parent or grandparent from whom the children inherited the condition.

Contributors to the guide were noted researchers, educators and practitioners in dermatology and pediatric dermatology from medical universities specializing in eczema and dermatitis. One contributor and review board member, Dr. David Olansky, MD, Assistant Clinical Professor, Emory University School of Medicine in Atlanta, explains, "The steroid-sparing effects of the Proteque approach, in my opinion, render its greatest usefulness as therapy with maintenance -- allowing us to either eliminate or reduce the exposure to potent steroids."

Brachman explains the terms "eczema" and "dermatitis" and the wide range of environmental allergens and irritants, at home and work, that trigger it -- including latex, rubber, plastic toys, soaps, lotions, jewelry, household cleaners, office copy paper, foods, preservatives, industrial chemicals, and medications. Changes in temperature and humidity, indoors and outdoors, also cause outbreaks. More factors, including rebound and side effects of steroid use, are detailed, along with how to prevent and manage the "itch that rashes"--eczema.

For more information about eczema, its causes, relief and prevention, newsletters, and a listing of 200+ dermatologists specializing in this steroid-sparing approach -- visit www.proteque.com or e-mail info@proteque.com. Proteque(R) SPS, for child and adult eczema prevention, relief and maintenance, can be ordered via Internet www.proteque.com, local US pharmacists, 200+ dermatologists, or 800-953-9250. Email: info@proteque.com

 

Press Release #10

NON-STEROID APPROACH TO MANAGE ECZEMA FOR CHILDREN AND PHYSICIANS PRESENTED AT NATIONAL PEDIATRIC CONFERENCES BY RALEIGH NCDERMATOLOGY COMPANY

RALEIGH, N.C., Dec. 4 /PRNewswire/ -- Thousands of Pediatricians at two recent conferences were provided with education about preventing and managing body, face and hand eczema symptoms for children and physicians -- without steroids. At the Infectious Diseases in Children Symposium in NYC, and the Chicago American Academy of Pediatrics meeting, pediatricians learned how to use a new approach and product, Proteque SPS Skin Protection Lotion, for managing recurring eczema symptoms -- itchy, dry, scaly, red patches of skin on the face, body, hands or feet. Approximately 10% of pediatric patients suffer with eczema or dermatitis and approximately 20-30% of Physicians suffer with hand eczema.

At the Symposium, Endicott NY pediatrician Dr. Mangala Puttanaih reported how she used non-steroid Proteque successfully, instead of typical topical corticosteroids, to manage her eczema patients and her own skin condition. "If you've treated an initial outbreak with topical or oral steroids, you can use Proteque SPS [Skin Protection System] to keep an outbreak of eczema from recurring," reports Dr. Katie Fine, a pediatrician at North Raleigh Pediatrics. Her recommendations are based on both clinical studies and family use with her son David's facial eczema and her own hand eczema.

Controlled clinical trials on prevention and treatment of dermatitis were completed in 1998 and 1999 by medical researchers at the University of California and North Carolina State University, respectively. Study results were published in Skin and Allergy News, Pediatric News, Medco Forum, and the medical journal, Skin Research and Technology 2000.

In the US, over 10,000 pediatricians, dermatologists, allergists, family practice physicians, and obstetricians now provide patient education materials and recommend this new steroid sparing approach to skin disease management to avoid typical side effects of ongoing topical and oral steroid use -- thinning of the skin, hyperpigmentation (discoloration), growth retardation, scarring, and even osteoporosis. According to Patty Brachman, a registered nurse and Vice President responsible for Professional Education at Proteque, "the key benefit is that patients, including children, babies, and adults, can use lower potency steroids or no steroids for managing their conditions to avoid these common side effects.

Proteque SPS (pronounced pro-tek) is a nonprescription, fragrance-free lotion with combined features of water-resistant skin protection, safe anti-inflammatory, anti-itch botanicals, and a proven antimicrobial ingredient. Proteque is available now through over 200 dermatology offices, toll-free 800-953-9250 or 888-840-7979, online at www.proteque.com, or may be ordered for delivery within 24 hours by any pharmacist. Physicians and pharmacies can order product from their wholesale supplier or directly at 800-953-9250 and online at info@proteque.com.

Proteque website www.proteque.com has extensive educational information for physicians, pharmacists, nurses and consumers. Proteque is a registered trademark of Proteque International with headquarters in Raleigh NC.

 

Press Release #9

NEW PROTEQUE NON STEROID APPROACH FOR ECZEMA CHILDREN INTRODUCED AT BOSTON PEDIATRIC CONFERENCE

RALEIGH, N.C., May 15 /PRNewswire/ -- Eczema (sometimes called dermatitis) is easy to diagnose--itchy, red, dry, peeling skin, sometimes with cracks or rash. It is incredibly sensitive, stings, burns and the pain makes babies and children (and some adults) cry and scratch. Hundreds of US and international pediatricians and pediatric dermatologists attending the American Academy of Pediatrics Conference in Boston discussed with Proteque International representatives their successful use of non-steroid, non- prescription Proteque(R) SPS (pronounced "pro-teck") as a steroid-sparing topical approach with a broad range of eczema and dermatitis patients.

"Eczema and dermatitis specialists from dermatology, neonatology and pediatric departments such as UCSF, Johns Hopkins, Stanford University and over 100 private pediatric and allergy practices recently reported positive pediatric and adult patient outcomes in actual patient use with this new steroid-sparing approach," said Fred Brachman, President and CEO of Protèque International. "Most common types of patient conditions were pediatric eczema and atopic and contact dermatitis including perioral and diaper dermatitis." The water-resistant dimethicone-based Proteque formula, with its four non- steroid anti-inflammatory and long-lasting antibacterial ingredients, reduced erythema, reduced transepidermal water loss, and killed Staph. Aueus and E.Coli according to pilot controlled clinical studies at UCSF Dept of Dermatology and NCSU. "Recommended alone, or as combination therapy with a lower potency corticosteroid, pediatricians and dermatologists prefer to prevent the recurrence of eczema and dermatitis instead of repeated use of debilitating strong topical or oral corticosteroids and antibiotics, which can cause thinning of the skin, scaring, osteoporosis and growth problems for children," Brachman said.

Proteque SPS is available now online at Planetrx.com (or phone via PlanetRX Customer Service 888-840-7979), at over 200 Dermatologist, Allergist & Pediatrician Offices or can be ordered by pharmacists directly from Protèque or from their wholesalers at most independent (Valu-Rite, Medicine Shoppe and Good Neighbor) and all major chain and grocery pharmacies, such as Wal-Mart, KMart, Walgreens, Kroger, Rite-Aid, Long's, Eckerd, Osco, Sav-On, Safeway, and CVS. More information including clinical research and ordering information is available at the http://www.proteque.com website or by calling 800-953-9250.

Proteque International's mission is to provide safer integrated approaches and solutions in eczema and dermatitis, especially for the professional and personal Pediatric healthcare community.

"Proteque is seeking immediate acquisition, merger, distribution or licensing relationships with other consumer and healthcare products companiesin the US and Internationally," said Brachman.

BOOTH #1818 Advancing Children's Health 2000 BOSTON sponsored by The American Academy of Pediatrics and the Pediatric Academic Societies. Hynes Convention Center, Boston MA, May 12-14.

Contact: Fred Brachman, Pres. & CEO 800-953-9250 or info@proteque.com

 

Press Release #8

PROTEQUE'S STEROID-SPARING APPROACH FOR ECZEMA SUFFERERS.

RALEIGH, N.C., April 17 /PRNewswire/ -- Eczema (sometimes called dermatitis) is easy to diagnose--itchy, red, dry, peeling skin, sometimes with cracks or rash. It is incredibly sensitive, stings, burns and the pain makes babies and children (and some adults) cry and scratch. Hundreds of US and international dermatologists and pediatric dermatologists attending the American Academy of Dermatology Conference in San Francisco, CA discussed with Proteque International representatives their expanded use of non-steroid, non- prescription Proteque(R) SPS (pronounced "pro-teck") as a steroid-sparing topical approach with a broad range of eczema and dermatitis patients.

"Eczema and dermatitis specialists from dermatology and pediatric departments such as UCSF, Johns Hopkins, Stanford University, and over 100 private practices reported positive pediatric and adult patient outcomes in actual patient use with this new steroid-sparing approach," said Fred Brachman, President and CEO of Proteque International. "Most common types of patient conditions were adult hand eczema, pediatric eczema, atopic and contact dermatitis, radiation and chemotherapy dermatitis, and diaper dermatitis."

The water-resistant dimethicone-based Proteque formula, with its four non- steroid anti-inflammatory and long-lasting antibacterial ingredients, reduced erythema, reduced transepidermal water loss, and killed Staph. Aueus and E.Coli according to pilot controlled clinical studies at UCSF Dept of Dermatology and NCSU. "Recommended alone, or as combination therapy with a lower potency corticosteroid, pediatricians and dermatologists prefer to prevent the recurrence of eczema and dermatitis instead of repeated use of debilitating strong topical or oral corticosteroids and antibiotics, which can cause thinning of the skin, scaring, osteoporosis and growth problems for children," Brachman said.

Proteque SPS is available now online at Planetrx.com (or phone via PlanetRX Customer Service 888-840-7979), at over 200 Dermatologist Offices or can be ordered by pharmacists from their wholesalers at most independent (Valu-Rite, Medicine Shoppe and Good Neighbor) and all major chain and grocery pharmacies, such as Wal-Mart, K Mart, Walgreens, Kroger, Rite-Aid, Long's, Eckerd, Osco, Sav-On, Safeway, and CVS. More information is available at the http://www.proteque.com website.

Proteque International's mission is to provide safer integrated approaches and professional solutions in dermatology, cosmeceuticals and immunology, globally. Proteque is seeking acquisition, merger and licensing relationships with other consumer and healthcare products companies in the US and Internationally.

SOURCE: Proteque International Web Site: http://www.proteque.com

 

Press Release #7

FATHER'S INTERNET SEARCH FINDS SOLUTION FOR DAUGHTER'S SUFFERING

RALEIGH NC-- Alison B. is taking piano lessons again. Because of a rare cell deficiency, the 15-year-old girl’s hands developed crippling contact dermatitis, also called hand eczema. Powerful steroid creams hardened the skin. The itching was so severe her father would find her awake at night rubbing her hands against a rough mat.

Alison’s problems began when she was seven years old. Her hands itched, which led to cracking and bleeding. She was diagnosed, by one physician, with Langerhan’s cell deficiency and allergies to the metals, such as nickel, found in jewelry, coins and clay. Doctors could offer little help. Langerhan’s cells play a role in the skin’s immunological response. "She was advised by specialists (rather unkindly) that she would not have a life like other children and would just have to put up with it,’’ said David, Alison’s father.

David turned to the Internet for answers and discovered Proteque, a new, non-steroid, over-the-counter skin product. It uses safe botanical ingredients to control inflammation, a water-resistant protectant to reduce water loss and prevent irritation, and an antimicrobial to kill Staph. Aureus and E. Coli. Clinical research testing results by dermatology experts at the University of California-San Francisco, presented at the Summer American Academy of Dermatology Conference in NYC, provides additional clinical evidence of Proteque’s effectiveness.

"The power of the Internet to, with a few taps on the keyboard, help people find disease management solutions to lifelong health problems such as Alison’s is what new companies like Protèque International and its E-Commerce partner, PlanetRx.Com, are about,’’ says Fred Brachman, president and CEO of Proteque International. "Awareness, availability, cost and convenience are key to patients and parents looking for solutions to their family health needs."

Before discovering Proteque, "My day-to-day life was severely affected,’’ recalls Alison. "Writing was difficult as the pen rubbed on the open places on my hand. ‘’ When the palms of her hands lost their elasticity from the crusting and cracking, she gave up playing the piano.

For years, Alison used expensive prescription steroid creams to control the inflammation, but their potency diminished with time. Other over-the-counter emollients and creams offered minimal help. Her parents even consulted a homeopathic practitioner. "He analyzed me as a "sulfur person’’ and I had to take a course of sulfur in distilled water. This did not have any benefit but it cost a lot of money.’’

Three months after the family’s successful Internet search, Alison wrote back: "Thank you so, so much for the cream! My hands have never been so good for so long in all my life. After living with contact dermatitis on my hands for 15 years I was not always able to participate in all the things my friends did. Now that I have started using it, I have found that I can. I used to be ashamed of my hands as they were always red, bleeding, cracking and weeping. The thought of living the rest of my life trying to hide my hands away from people's view was very distressing. I never thought there would be a cream that would make it go away. I am more confident.''

Alison says the product is still working. "I know,'' says Alison. "that it is not a cure for the skin dermatitis, but it has certainly made my life easier."

A new partnership with www.PlanetRx.com, the online supplier of Protèque, provides 24 hour order service and toll-free (888-840-7979) customer service. Proteque’s web site is www.proteque.com and customer service is 800-953-9250.

About PlanetRx.com

PlanetRx.com, Inc. (www.planetrx.com) is a leading online healthcare destination for commerce, content, and community. PlanetRx.com, which launched its e-commerce website on March 18, 1999, provides a convenient, private, and informative shopping experience for health and personal care products.

About Protèque International

Proteque International is dedicated to finding new, economical and safer approaches to prevent and treat eczema and irritant contact dermatitis, with focus on Hands, Body, Face and Feet eczema and contact dermatitis. Its approach is to augment current steroid and moisturizer therapies with complementary "steroid-sparing" technologies and ingredients for skin disease management.

Contacts: Fred Brachman, President or Patty Brachman, RN, Vice President 800-953-9250 info@proteque.com

 

Press Release #6

UCSF RESEARCHERS REPORT ON NON-STEROID TO PREVENT DERMATITIS AT AAD CONFERENCE

RALEIGH NC -- University of California, San Francisco researchers reported on a new All-in-one Non-Steroid Lotion, called Protèque, to prevent skin irritation, called contact dermatitis, at the American Academy of Dermatology meeting in NYC. The research is part of a new "steroid sparing" approach to prevent recurrence of eczema and irritant contact dermatitis using a preventive products without steroid. The successful pilot clinical research results were presented Hongbo Zhai, MD, research dermatologist at University of California-San Francisco.

"The non-prescription Protèque skin protection lotion is recommended by dermatologists and pediatricians to prevent ICD (irritant contact dermatitis) in home or work environments, where skin irritants, even topical corticosteroids, may induce ongoing dermatitis or eczema conditions,’’ said the study’s authors. The unique formulation contains a combination of a water-resistant protectant with botanical anti-inflammatory and antimicrobial ingredients.

The researchers applied the skin protectant Proteque on the arm creases of 12 volunteers, then – 30 minutes later – rubbed on sodium lauryl sulfate (SLS) as the irritant. SLS is also the primary cleansing agent found in virtually all shampoos and soaps. On the other arm crease spots, the researchers rubbed on SLS directly or used a different control formulation, without the active dimethicone, and then added SLS. In visual scoring tests, the Proteque-treated spots showed statistically significant less irritation over a five-day period compare to double-blind controls. Proteque treated skin also lost less water, a key measure of skin health.

Next up: Researchers say they want to formally validate Proteque’s effectiveness in real-world situations. Chronic ICD is typically caused by constant exposure to low levels of irritants. "The current model data should be validated in the actual workplace or home environment,’’ said the study’s authors.

Since the pilot clinical study was completed, over 5,000 dermatologists, pediatricians, podiatrists, family practioners, and Ob-Gyns have started using the Protèque SPS skin protectant product, which is non-prescription, by itself or over the top of corticosteroids, on adults, children and their medical staff with hand or body eczema and dermatitis conditions. What is most important to the physicians and the patients is that they find an alternative "steroid-sparing" economical approach that reduces the risks of overuse or prolonged use of steroids for adults and especially for children.

Protèque is available through dispensing dermatologists or can be special ordered from major drug wholesalers at the pharmacy counters. Consumers can also order Protèque directly, without a prescription, on the internet at www.PlanetRx.com or call, toll-free, 24 hours a day 1-888-840-7979.

Physicians and consumers may call 800-953-9250 or visit www.proteque.com for research results and more information about the product for staff and patients with eczema and dermatitis conditions.

CONTACT:

Fred Brachman, President -or-Patty Brachman, RN, Vice President

Proteque International

800-953-9250

info@proteque.com website: www.proteque.com

 

Press Release #5

NEW NON-CORTICOSTEROID PROTEQUE LOTION TO REDUCE SKIN IRRITATION AND UVB SUN DAMAGE PRESENTED BY SKIN EXPERT AT HAWAII CONFERENCE.

MAUI, Hawaii, Feb. 26 /PRNewswire/ -- "This pilot clinical research is the
first to confirm the efficacy of a non-steroid OTC skin protectant lotion that
also reduces irritant contact dermatitis effects and UVB-induced skin
irritation," reported Dr. Nancy Monteiro-Riviere at the Hawaii Skin Foundation
Meeting last week. Such results are of particular interest to physicians who
treat eczema and irritant contact dermatitis patients.

The studies, performed at the internationally recognized Center for Cutaneous
Toxicology and Pharmacology at North Carolina State University, assessed the
ability of Proteque to modulate contact dermatitis. The results showed that
Proteque SPS lotion significantly blocked erythema, especially when applied
after sodium laurel sulfate (SLS) dosing. In addition, Proteque, with no sun
screen filter ingredients, reduced UVB-induced sunburn cell formation from 50
to 3, and reduced histological index of skin damage significantly. This study
at NCSU followed a pilot clinical study by consultants Dr. Hongbo Zhai and Dr.
Howard Maibach, at the University of California San Francisco, Dermatology
Dept. showing statistically significant reduction of erythema and
transepidermal water loss. That clinical study will be presented at the
American Academy of Dermatology in July 1999.

Several of the 350 Dermatologists who attended the conference described
Proteque SPS as the skin protectant lotion they use successfully for eczema
and irritant contact dermatitis patients, with or without corticosteroids.
While they began by using it primarily for hand eczema disease management,
they have also found it useful for body, feet and face. Patients, they say,
also appreciate that it is non-greasy, water resistant and only needs applying
twice a day.

Over 2,000 US private practice and hospital-based dermatologists,
pediatricians, family and general practice and OB/GYNs in California, Texas,
Ohio, Pennsylvania, Maryland and North Carolina are using Proteque for their
staff and patients. Proteque SPS is also used by physicians as a new steroid-
sparing approach to help children, pregnant women and adults who physicians
believe should limit exposure to the risks of corticosteroid use as much as
possible.

Proteque International officially launched its first product through private
dispensing dermatologists, dermatologist-approved Kaiser Permanente
pharmacies, and the three largest nationwide pharmacy wholesalers in January
after three years of laboratory and market research and collaboration with
leading pharmaceutical, regulatory and cosmetic science experts.

The company is seeking additional qualified private investors and global and
US strategic partners with interests in non-steroid eczema and irritant
contact dermatitis solutions.

For more in-depth information about the company, product and research, visit
its website at www.proteque.com, or send e-mail to info@proteque.com, or phone
800-953-9250.

SOURCE Proteque International

CO: Proteque International

ST: Hawaii

IN: HEA MTC

SU: PDT

02/26/99 06:30 EST http://www.prnewswire.com

 

Press Release #4

For Further Information Contact:
Fred Brachman (1-800-953-9250)

February 1, 1999/Raleigh, NC

PROTEQUE TALKS "SKIN SENSE" ON TV IN PA

Protèque Hands, Body, Face and Feet Lotion, a new skin protectant now available through dermatologists, and pharmacies, is being featured on the syndicated television program "Skin Sense" starting Tuesday, February 2 with Dr. Stephen Schleicher, nationally noted dermatology researcher, author and expert on hand dermatitis treatment and prevention.

This 30 minute TV program focuses on what the general public does not know -- that daily chemical irritants, at work and at home, found in soaps, recycled paper in offices, protective latex gloves, hair products, and now alcohol in the new antibacterial hand sanitizers all contribute to what one dermatologist, Dr. Stacy Miller of Raleigh NC, described as the worst year of hand eczema in his 35 year medical career. This broadcast is the first in the US to provide viewers with educational information about an explosive demographic growth in this skin disease condition affecting an estimated 10 to 20% of the US population, mostly women, and causing millions of professionals such as dentists, nurses, surgeons, hair dressers, housekeepers, bakers and chefs to quit their professions or experience a loss of productivity. Unfortunately new moms, and some dads, who wash their hands frequently suffer for the first time in their lives with this condition but can't quit that "job" as caretaker for their newborn infants.

Proteque is described by dermatologists and researchers as the first non-steroid water-resistant, non-greasy protective cosmeceutical which prevents skin irritation due to frequent handwashing and irritant chemicals. It also delivers anti-inflammatory and antimicrobial ingredients that relieve itchy, cracked, red, rash, dry skin symptoms on fingers, hands and feet. Physicians are using it in combination with corticosteroids, or by itself, as a more effective long-term steroid-sparing treatment.

Dr. Schleicher will discuss with Fred Brachman, President and CEO of Protèque International, Inc., the uses of Proteque recommended by over 1,000 US dermatologists, in the last 12 months in selected market tests on physicians, nurses and patients with hand dermatitis, also called "hand eczema."

"PAXTV and Time Warner Cable, throughout northeastern Pennsylvania, will broadcast a comprehensive discussion of this healthcare problem and new medical approach to the general public for the first time, " Brachman said. Product market tests with over 1,200 Dermatologists, primarily in California, Hawaii, Texas and Ohio were completed last December. Brachman also noted that, "More than 1,000 General and Family Practitioners, Pediatricians and OB/GYNs and Allergists have requested samples of Proteque's non-steroid over-the-counter Skin Protection System for patients with hand and body eczema."

A recent report by the National Institute of Occupational Safety and Health (NIOSH), in December 1998, identified irritant contact dermatitis as one of its top priority occupational health diseases in the U.S.

"Proteque International completed its confidential pilot clinical and laboratory studies in 1998, conducted by international dermatology and infection control authorities at University of California, Duke University, BioScience Laboratories in Bozeman, MT, Cutaneous Toxicology and Pharmacology at North Carolina State University and antimicrobial experts in Switzerland. Until now, Protèque International has concentrated its research and educational campaign on the 6,000 US Dermatologists, who specialize in treating this increasing national personal healthcare and occupational health problem.

Historically, the 200,000 General Practice physicians, Pediatricians and OB/GYN who see the most patients with hand dermatitis and eczema problems often fail to get satisfactory long-term results with traditional prescription Corticosteroids and moisturizer therapies.

The company being featured in the program, Proteque International, with headquarters in Raleigh, NC, is seeking strategic alliance partners, qualified private investors, venture capital partners and global distributors who have an interest and experience in pharmaceutical, personal healthcare consumer products, occupational health and safety or cosmeceutical companies. These, in turn, should be focused on skin disease management, dermatology, pediatric, allergy, glove protection segments of the hospital, healthcare, HMO, clean room, laboratory, veterinary and dental supply markets.

Proteque International can be contacted by e-mail at info@proteque.com, and extensive information is available on its website www.Proteque.com.

Proteque International is dedicated to finding new, economical and safer approaches to prevent and treat eczema and irritant contact dermatitis, with a special focus on the hands. Its approach is to augment current steroid and moisturizer therapies and latex and non-latex glove protection with proven safer technologies for cleansing and skin protection.

 

Press Release #3

August 8, 1998/Raleigh, NC

Medecon Introduces To Its Members Protèque®  For Hand Eczema And Irritant Contact Dermatitis For Staff And Patients.

ATTENTION: Dermatology, Employee Health, Infection Control, Nursing Management

Subject: MEDECON launches New Non-Steroid OTC Product Contract with 30% Discount on PROTÈQUE® for Staff and Patient Hand Eczema and Irritant Contact Dermatitis -- Prevention and Treatment (in conformance with APIC recommended standards for handwashing and protective glove use).

Since official launch of PROTÈQUE® at the March 1998 American Academy of Dermatology Conference in Orlando, over 450 dermatologists have started recommending and dispensing Protèque to Employee Health, Staff and Patients at such institutions as Duke U., John Hopkins, NIH, Emory University Hospitals and hundreds of other healthcare facilities. Over 15,000 users have responded with very positive feedback consistent with clinical study results including reduced erythema, itching, TEWL and other symptons characteristic of hand eczema and irritant contact dermatitis. For chronic cases, physicians are recommending Protèque’s use during the day, when patients/employees are exposed to irritants and frequent washing, and topical corticosteroids at night. Protèque thereafter becomes the daily maintenance and prevention therapy at a very low cost and high compliance rate of only 2 applications per day.

Antimicrobial testing by a leading international testing authority documented six hours of antimicrobial effectiveness through repeated washings and exposure to both Staph. Aureus and E. Coli bacteria. Of course this is of greatest value to healthcare workers (and patients) in physician offices, hospitals and nursing homes, but also food handlers with hand eczema conditions. Protocols continue to require frequent proper handwashing and glove protection, but this additional protection of staff and patients is an integral part of the overall solution to skin disease management and prevention.

Occupational workers seeing the greatest value from Protèque are nurses, laboratory technicians, pharmacists, food handlers (with or without gloves), dentists/hygienists, surgeons, housekeepers, and even office workers with paper allergies -- most wash their hands frequently and are exposed to many chemicals in soap, gloves and medical product..

The official FDA labeling indication: Helps prevent and temporarily protects chafed, chapped, cracked or wind-burned skin. However, noted dermatology researcher and consultant Dr. Howard Maibach’s reported successful "Prevention of Irritant Contact Dermatitis" in clinical results on double-blinded controlled studies at the University of California. Also, Dr. Nancy Monteiro-Riviere at NCSU Cutaneous Pharmacology and Toxicology just completed new studies showing positive results of Protèque as a non-steroid for "Treatment of Irritant Contact Dermatitis."

Protèque® Skin Protectant Lotion is a new generation of integrated phytochemicals (botanicals), antimicrobial and water-resistent protection with anti-inflammatory characteristics for use by:

1) physicians, nurses,pharmacists, laboratory technicians and staff (including office workers)

2) patients with dry irritated, cracked, chapped, chafed, fissured, itchy skin especially on the hands

referred to by most physicians as irritant contact dermatitis or hand eczema. (Also for feet, body and

face use.)

3) children and infants with either irritant contact dermatitis, rashes or

recurring eczema-type skin conditions on the hands, body, arms, legs and feet

4) elderly or physically disabled immobile patients with skin irritation problems

PLEASE CALL 800-953-9250 CUSTOMER SERIVICE HOT LINE TO ORDER OR TO ANSWER QUESTIONS. We will be pleased to provide you the product at wholesale discounted price to carry in Central Supply, Physician Offices, Employee Health and Pharmacies for staff and patients.

Visit the PROTEQUE web site at www.proteque.com for more information and links to many research sources on the topic of prevention and treatment of hand eczema and irritant contact dermatitis.



Press Release #2

May 13, 1998/Raleigh, NC

Diversified Network Services (DNS) Announces Contract Award To New Contact Dermatitis Disease Management Company-- Protèque International

Diversified Network Services awarded Protèque International a two-year contract for products focused on irritant contact dermatitis disease management—the leading occupational disease in the US according to recent reports by the National Institute of Occupational Health and Safety. Under the contract agreement, Protèque™ Skin Protection System products will be distributed to its member physician, hospital, long-term care, pharmacy, and laboratory organizations throughout the US. Protèque Skin Protectant products, which have been clinically tested by notable dermatology research organizations, are used by staff and patients for both the prevention and treatment of skin irritation conditions described by dermatologists as irritant contact dermatitis or eczema, usually on the hands.

Anthony Caliguri, Assistant VP, Shared Services Program, announced the relationship with Protèque and will be communicating the availability of these products to all its members over the next few months. Educational materials and samples are being distributed to 1250 physician group practices to offer the new product, Protèque Skin Protectant Lotion, for both staff and patients with these irritated skin conditions, often caused by frequent handwashing, soaps, gloves, or chemicals. Another application is for prevention and treatment of skin irritation relating to incontinence found in nursing homes, hospitals, and infants – sometimes called diaper dermatitis. This non-steroid product, a lotion for both the hands and body, is being used alone and in combination with traditional corticosteroids by physicians treating eczema conditions and later as a preventive maintenance therapy for skin protection.

Diversified Network Services (DNS) Shared Services Program is dedicated to providing member participants with high quality products and services from reputable vendors. The Program s innovative products and services are a result of membership in two supergroups, Mid-Atlantic Group Network of Shared Services (MAGNET) and the Shared Services Healthcare Inc. (SSH) of Atlanta GA. MAGNET represents 840 acute hospitals (100,000 beds); 1,100 long-term care facilities; 9,000 physicians and 400 alternative care agencies. SSH, Inc., serves more than 1,069 healthcare facilities in 10 southeastern states: Alabama, Georgia, Florida, Mississippi, Louisiana, Tennessee, Virginia, North Carolina, South Carolina, and Texas. 

DNS also has affiliated independent pharmacies, laundries, food services, housekeeping and laboratories as prospective users of Protèque’s skin protection products. DNS has a strong commitment to educating member employees and management in areas of disease management and outcomes management resulting in overall reduction of healthcare costs. Protèque International will help develop valuable educational programs in the area of skin disease management.

Protèque International educational information about contact dermatitis disease management is available on the Internet at www.proteque.com. or 800-953-9250. DNS Members can order product directly from Protèque’s Customer Service Department under this new contract effective May 1, 1998.

Contacts:

Patricia Brachman, RN, Protèque International 800-953-9250 Call 8:30am to 5:30pm EST M-F

Fred L. Brachman, President, Protèque International, 800-953-9250

Anthony J. Caliguri, Assistant Vice President, Diversified Network Services (203) 294-7322

 

Press Release #1

For Further Information Contact:
Thack Brown (910) 575-2635 or
Fred Brachman 800-953-9250

CLINICAL STUDY PROVES NEW SKIN PROTECTANT TO BE COMPATIBLE WITH ANTIMICROBIAL SCRUB SOAPS USED IN HOSPITALS

Raleigh NC /February 18, 1998/PR Newswire/ Protèque International today reported results of a human clinical research study by BioScience Laboratories, proving Protèque Hands, Body, Face and Feet Lotion compatible with Chlorhexidine Gluconate hospital scrub soaps. This announcement is a prelude to the launch of this new skin protectant at the American Academy of Dermatology annual conference in Orlando starting February 28, 1998. (A preliminary "soft launch" at the Hawaii Dermatology Seminar in Hawaii, Feb 2, 1998, was enthusiastically received by hundreds of practicing dermatologists as a welcome alternative to traditional post-treatment use of moisturizers and steroids by patients with irritated skin conditions.)

During last summer's Association of Professionals in Infection Control and Epidemiology annual meeting, scientific evidence was presented showing that traditional hand lotions undermine the antimicrobial effectiveness of surgical scrub soaps. As a result, hospitals throughout the country instituted policies prohibiting use of hand lotions by surgical personnel until product compatibility could be proven.

Dr. Daryl S. Paulson, President and CEO, BioScience Laboratories, reported on February 12, 1998: " Preliminary results obtained in a pilot study indicate that Protèque Hands, Body, Face and Feet Lotion does not adversely affect the antimicrobial properties of 4% Chlorhexidine Gluconate surgical scrub. The effects of this skin protectant on surgical gloves were also evaluated as part of the pilot study. Once again, preliminary results indicate that the glove integrity is not affected by use of Protèque in conjunction with a 4% Chlorhexidine Gluconate surgical scrub."

"Infection Control professionals in hospitals across the country will find this study's results important", said Fred Brachman, President of Protèque International, Inc., " because so many healthcare professionals who use antimicrobial scrub soaps suffer from skin irritation known to dermatologists as chronic hand contact dermatitis or eczema. Classic symptoms are dryness, itchiness, redness, irritation, cracking and pain. Protèque, in compliance with the FDA monograph for skin protectants, provides a new prevention solution."

After years of product development and market testing on thousands of healthcare professionals, including dental office workers and laboratory professionals, Protèque International will begin distributing its professional line in March 1998. Distribution initially will be directly through Dermatologists and medical suppliers to major Hospitals, HMO's and PPO's concerned with contact dermatitis disease management and prevention. Protèque is in discussions with a number of medical supply distributors and major hospital buying groups to make the product readily available throughout the US.

What makes Protèque Hands, Body, Face and Feet Lotion particularly valuable is that it only needs to be applied 2-3 times per day and it delivers, through repeated washings, a combination of invisible protectant, therapeutic anti-irritant, and antimicrobial benefits in an all-in-one OTC (over-the-counter) non-greasy, long-lasting formula. The first product on the market, Protèque Hands, Body, Face and Feet Lotion, has a suggested retail price of $15.00 for 240 applications, which lasts the average users 3-4 months. Mr. Brachman said, "Our pricing objective is to make the product affordable to anyone who needs it, especially the 2.2 million nurses and 1 out of 20 US workers who suffer from this dangerous and painful occupational disease."

Information about this new company, which is focused on the prevention and treatment of irritant contact dermatitis, will be available at the American Academy of Dermatology Meeting Feb. 27-Mar. 4, 1998. Protèque International can be reached through its customer service number (800-953-9250), and its internet web site (www.proteque.com).

Protèque International's mission is to provide integrated systems and solutions for professional and consumer skin protection, globally. Protèque International works with leading research, medical and healthcare provider organizations to set the standards for quality, safety and effectiveness of integrated skin protection and delivery systems.

[Company Information] [Research Results] [Product Information] [New Information]
[How to Contact Us] [Physician Education] [Consumer Education] [Press Releases] [Home]
Copyright ©2004 by Protèque International